HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl orthoformate → HCID 178428087, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | HCID 57488490 | HCID 57488490 | — |
| Product | HCID 178428087 | HCID 178428087 | — |
Reaction Steps
The (S)-3-(3,4-diamino-5-methylphenyl)-4-phenyloxazolidin-2-one was dissolved in triethyl orthoformate and was refluxed for 30 minutes. After cooling the excess of triethyl orthoformate was removed under reduced pressure. The final product was purified via FPLC using a chloroform-methanol gradient (0→10%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09173885B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-3157ec96755e4cbb9a66ec4ce5852e0a |
| Source note | uspto-grants-2015_11 |