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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 706556Generated: October 29, 2026

2-(Chloromethyl)-6-isopropylpyridine hydrochloride → 3-chloro-1-((6-cyclopropylpyridin-2-yl)methyl)-4-nitro-1H-indazole

https://huagongshe.com/reaction/706556

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-6-isopropylpyridine hydrochlorideHCID 67974153—
Reactant2-(Chloromethyl)-6-cyclopropylpyridine hydrochlorideHCID 67974654—
ReactantHCID 178526560HCID 178526560—
Product3-chloro-1-((6-cyclopropylpyridin-2-yl)methyl)-4-nitro-1H-indazoleHCID 8669932372%

Reaction Steps

Prepared according to Preparation D, Step D, substituting 3-chloro-4-nitro-1H-indazole for 3-bromo-4-nitro-1H-indazole and 2-(chloromethyl)-6-cyclopropylpyridine hydrochloride for 2-(chloromethyl)-6-isopropylpyridine hydrochloride, to give the title compound (72%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09174981B2
Source datasetuspto-grants-2015_11
ORD IDord-f69ccf17c737477fa089d303b158520a
Source noteuspto-grants-2015_11