HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 7-fluoroimidazo[1,2-a]pyridine-3-carboxylate → 7-bromo-N-(3-methyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 7-fluoroimidazo[1,2-a]pyridine-3-carboxylate | HCID 67259301 | — |
| Reactant | Methyl 7-bromoimidazo[1,2-a]pyridine-3-carboxylate | HCID 67259752 | — |
| Reactant | 1-((6-isopropylpyridin-2-yl)methyl)-3-methyl-1H-indazol-4-amine | HCID 67974642 | — |
| Product | 7-bromo-N-(3-methyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide | HCID 67976410 | 62% |
Reaction Steps
Prepared according to Example 1, Step A, substituting 3-methyl-1-((6-methylpyridin-2-yl)methyl)-1H-indazol-4-amine for 1-((6-isopropylpyridin-2-yl)methyl)-3-methyl-1H-indazol-4-amine and methyl 7-bromoimidazo[1,2-a]pyridine-3-carboxylate for ethyl 7-fluoroimidazo[1,2-a]pyridine-3-carboxylate, to give the title compound (62%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09174981B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-dc793c96b0944272b89a40ac62064283 |
| Source note | uspto-grants-2015_11 |