Imidazo(1,2-a)pyridine-3-carboxylic acid → N-(1-((tetrahydro-2H-pyran-2-yl)methyl)-1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide

Participants

Role	Name	HCID	Charge
Reactant	Imidazo(1,2-a)pyridine-3-carboxylic acid	HCID 73142	—
Reactant	1-(2,4-difluorobenzyl)-1H-indazol-4-amine	HCID 67976107	—
Reactant	1-((tetrahydro-2H-pyran-2-yl)methyl)-1H-indazol-4-amine	HCID 67976164	—
Product	N-(1-((tetrahydro-2H-pyran-2-yl)methyl)-1H-indazol-4-yl)imidazo[1,2-a]pyridine-3-carboxamide	HCID 86699344	—

Reaction Steps

Prepared according to the method of Example 109, replacing 7-(2-methoxyethoxy)imidazo[1,2-a]pyridine-3-carboxylic acid and 1-(2,4-difluorobenzyl)-1H-indazol-4-amine with imidazo[1,2-a]pyridine-3-carboxylic acid and 1-((tetrahydro-2H-pyran-2-yl)methyl)-1H-indazol-4-amine, respectively. MS (APCI) m/z=376 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09174981B2
Source dataset	uspto-grants-2015_11
ORD ID	ord-998eaefd3d9e4c5da773d2c6c4e09765
Source note	uspto-grants-2015_11