HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3,4-Dinitrobenzyl)-4-methylpiperazine → 1-(3,4-Diaminobenzyl)-4-methylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3,4-Dinitrobenzyl)-4-methylpiperazine | HCID 59139007 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | N,N-dimethylformamide methanol | HCID 21901440 | — |
| Product | 1-(3,4-Diaminobenzyl)-4-methylpiperazine | HCID 59127396 | — |
Reaction Steps
1-(3,4-Dinitrobenzyl)-4-methylpiperazine (2.8 g, 10 mmol), was dissolved in DMF:MeOH (1:1, 20 mL) and agitated with 10% Pd/C (280 mg) under an atmosphere of H2 for 12 hrs. The reaction was monitored by TLC. The mixture was then filtered and evaporated to give a dark solid which was used immediately without any further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09174996B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-d01f493d1dd74d0699761146494f282f |
| Source note | uspto-grants-2015_11 |