HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ninhydrin → 6-Carboxyfluorescein succinimidyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ninhydrin | HCID 10236 | — |
| Reactant | 6-Carboxyfluorescein | HCID 76806 | — |
| Reactant | HCID 21988380 | HCID 21988380 | — |
| Product | 6-Carboxyfluorescein succinimidyl ester | HCID 2762614 | — |
Reaction Steps
The resin was treated with 2 equivalents 6-FAM-NHS in 1% DIEA/DMF and stirred or shaken at ambient temperature overnight. When complete, the resin was drained, washed thrice with DMF, thrice with (1×DCM and 1×methanol) and dried to provide an orange resin that was negative by ninhydrin test.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09174982B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-bac6a572c564423b92b0c10d59306817 |
| Source note | uspto-grants-2015_11 |