HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenyl 4-carbamoylphenylcarbamate → 4-[({4-[4-{4-[(Methylcarbamoyl)amino]phenyl}-6-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1,3,5-triazin-2-yl]phenyl}carbamoyl)amino]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenyl 4-carbamoylphenylcarbamate | HCID 60631229 | — |
| Reactant | 1-(4-(4-(4-Aminophenyl)-6-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1,3,5-triazin-2-yl)phenyl)-3-methylurea | HCID 67437223 | — |
| Product | 4-[({4-[4-{4-[(Methylcarbamoyl)amino]phenyl}-6-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1,3,5-triazin-2-yl]phenyl}carbamoyl)amino]benzamide | HCID 67021914 | 13% |
Reaction Steps
The title compound was prepared by following the procedure of example 462 step 7 using 1-(4-(4-(4-aminophenyl)-6-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1,3,5-triazin-2-yl)phenyl)-3-methylurea and phenyl 4-carbamoylphenylcarbamate. Yield 90 mg, 13% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09174963B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-95642954d2d4433b854dfa3d9c4f9374 |
| Source note | uspto-grants-2015_11 |