Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 707929Generated: October 30, 2026

1-(2-Pyrimidinyl)piperazine → HCID 58203801, compound

https://huagongshe.com/reaction/707929

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyrimidinyl)piperazineHCID 88747—
Reactant8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acidHCID 58203883—
ProductHCID 58203801HCID 58203801—

Reaction Steps

Following the procedure for 103, 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (50.0 mg, 0.2 mmol) was reacted with 2-(piperazin-1-yl)pyrimidine (1.2 equiv) to give 177 (8.7 mg, M+1 460.1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09175009B2
Source datasetuspto-grants-2015_11
ORD IDord-9db3fdb9377e4da08d05f9cae0a843c7
Source noteuspto-grants-2015_11