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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 707936Generated: October 30, 2026

1-(Tetrahydro-2-furoyl)piperazine → HCID 58203896, compound

https://huagongshe.com/reaction/707936

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Tetrahydro-2-furoyl)piperazineHCID 2734641—
Reactant8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acidHCID 58203883—
ProductHCID 58203896HCID 58203896—

Reaction Steps

Following the procedure for 103, 8-(1H-Pyrazol-4-yl)-4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene-2-carboxylic acid (50.0 mg, 0.2 mmol) was reacted with piperazin-1-yl(tetrahydrofuran-2-yl)methanone (1.2 equiv) to give 184 (19.3 mg, M+1 480.1)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09175009B2
Source datasetuspto-grants-2015_11
ORD IDord-03dc7e9b562a44269a9931166cd32ec8
Source noteuspto-grants-2015_11