HRID708042

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID23062080

Oxetan-3-amine--hydrogen chloride (1/1)

C3H8ClNO

结构：Nc1nc(-c2cc3c(s2)-c2ccc(C(=O)O)cc2OCC3)n(-c2ccc(F)cc2F)n1

HCID67050538

未命名化合物

PRODUCTS

生成物

结构：Nc1nc(-c2cc3c(s2)-c2ccc(C(=O)NC4COC4)cc2OCC3)n(-c2ccc(F)cc2F)n1

HCID58204058

未命名化合物

PROCEDURE

实验过程

Similarly to as described in General Procedure D, 2-[5-Amino-2-(2,4-difluoro-phenyl)-2H-[1,2,4]triazol-3-yl]-4,5-dihydro-6-oxa-1-thia-benzo[e]azulene-8-carboxylic acid was reacted with 3-aminooxetane hydrochloride to give 297 as a colorless solid after reverse phase HPLC (146 mg). LCMS: 496.1