HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67208761, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 59607675 | HCID 59607675 | — |
| Product | HCID 67208761 | HCID 67208761 | — |
Reaction Steps
To tert-butyl 4-(biphenyl-4-yl)-3-(tert-butoxycarbonylamino)butanoate (110 mg, 0.267 mmol), a solution of 4 M HCl in 1,4-dioxane (0.668 ml, 2.67 mmol) is added. After stirring for 1 h, the reaction mixture is concentrated to give crude 3-amino-4-biphenyl-4-yl-butyric acid tert-butyl ester hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822534B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-d1e57d16ae2146cebccf0bfb4c8aaff0 |
| Source note | uspto-grants-2014_09 |