HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalyl chloride → Dimethyl-1,3-oxazole-5-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | Dimethyl-1,3-oxazole-5-carboxylic acid | HCID 1132979 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Dimethyl-1,3-oxazole-5-carbonyl chloride | HCID 12336332 | — |
Reaction Steps
To a stirring solution of 2,4-dimethyl-oxazole-5-carboxylic acid (30 mg) in DCM (2.0 mL), oxalyl chloride (3.0 eq) was added at room temperature. The reaction mixture was stirred for 30 minutes. Solvents were evaporated and dried under vacuo to afford 2,4-dimethyl-oxazole-5-carbonyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09175003B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-051aa11aea3d49acb73551ed03209563 |
| Source note | uspto-grants-2015_11 |