HCID 118098687, compound → HCID 118098685, compound

Participants

Reaction Steps

To a solution of 3A (2.2 g, 6.14 mmol) in MeOH (50 ml) and EtOAc (50.0 ml) was added 10% Pd on carbon (0.653 g, 0.614 mmol) and the mixture was stirred under a hydrogen balloon for 2 h. Pd/C was removed by filtration. The filtrate was concentrated to give 3B that was used for next step without further purification. 1H NMR (400 MHz, CDCl3) δ ppm 7.75 (d, J=8.35 Hz, 1H) 6.58-6.67 (m, 1H) 6.52 (s, 1H) 4.78 (s, 2H) 3.04-3.13 (m, 2H) 2.94 (s, 3H) 1.45 (d, J=39.11 Hz, 9H) 1.26 (t, J=7.47 Hz, 3H).

Provenance & Evidence