HCID 59315011, compound → HCID 59315233, compound

Participants

Reaction Steps

To a 500 mL round-bottomed flask was added tert-butyl 2-(isopropylsulfonyl)-5-nitrobenzyl(methyl)carbamate (2.6 g, 6.98 mmol, see WO 2008/079836 for preparation) and MeOH (200 ml) to give a colorless solution. Pd/C (0.074 g, 0.698 mmol) was added. The mixture was stirred under a hydrogen balloon at rt overnight. Pd/C was removed by filtration and the filtrate was concentrated to give 8A (2.18 g, 91% yield).

Provenance & Evidence