Sodium Hydroxide → HCID 118098722, compound

Participants

Reaction Conditions

Reaction Steps

13B (820 mg, 1.685 mmol) was dissolved in EtOH (20 mL), sodium hydroxide (8.43 mL, 16.85 mmol) was added. The reaction mixture was stirred at 100° C. for 1 h. The mixture was concentrated, acidified to pH 2 with 1N HCl; extracted with EtOAc. The organic layer was washed with brine, dried and concentrated gave 13C (620 mg, 1.605 mmol, 95% yield). MS (ESI) m/z: 386.9 (M+H)+.

Provenance & Evidence