HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 708929Generated: October 30, 2026
Potassium Acetate → HCID 131733887, compound
https://huagongshe.com/reaction/708929
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Acetate | HCID 517044 | — |
| Reactant | Bis(neopentyl glycolato)diboron | HCID 2734316 | — |
| Reactant | HCID 118093013 | HCID 118093013 | — |
| Catalyst | Bis(cyclopenta-1,4-dien-1-yl(diphenyl)phosphane);dichloropalladium;iron(2+) | HCID 178418228 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 131733887 | HCID 131733887 | 55.7% |
Reaction Steps
To a reaction tube was added 39C (770 mg, 1.223 mmol), 5,5,5′,5′-tetramethyl-2,2′-bi(1,3,2-dioxaborinane) (332 mg, 1.468 mmol), KOAc (300 mg, 3.06 mmol), and Pd(dppf)Cl2 (201 mg, 0.245 mmol) in DMSO (10 ml). The tube was filled with Ar, sealed and stirred at 85° C. for 2 h. The mixture was quenched with H2O, and extracted with EtOAc (3×). The combined organic layers was filtered though silica gel and concentrated. The residue was purified by prep HPLC to give 39D (405 mg, 0.681 mmol, 55.7% yield) as a tan solid. MS (ESI) m/z: 595.4 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09174974B2 |
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| Source dataset | uspto-grants-2015_11 |
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| ORD ID | ord-2da2ab9bc3774d038bd5e71d2a7345ee |
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| Source note | uspto-grants-2015_11 |
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