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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709026Generated: October 31, 2026

1-(Bromomethyl)-3-(trifluoromethyl)benzene → 2,3-Dimethoxy-5-{[3-(trifluoromethyl)benzyl]sulfanyl}pyridine

https://huagongshe.com/reaction/709026

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-3-(trifluoromethyl)benzeneHCID 123061—
Reactant5-(3-Chlorobenzylthio)-2,3-dimethoxypyridineHCID 71185833—
Product2,3-Dimethoxy-5-{[3-(trifluoromethyl)benzyl]sulfanyl}pyridineHCID 71186459—

Reaction Steps

Prepared as described for 5-(3-chlorobenzylthio)-2,3-dimethoxypyridine (Intermediate 8) but using 1-(bromomethyl)-3-trifluoromethylbenzene instead of 1-(bromomethyl)-3-chlorobenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-9387356102744658a680f5c257e6666e
Source noteuspto-grants-2015_11