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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709037Generated: October 31, 2026

Picolyl chloride → 3-(Methoxymethoxy)-1-(methoxymethyl)-5-[(pyridin-2-ylmethyl)sulfanyl]pyridin-2(1H)-one

https://huagongshe.com/reaction/709037

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPicolyl chlorideHCID 23393—
Reactant5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-oneHCID 86731527—
Product3-(Methoxymethoxy)-1-(methoxymethyl)-5-[(pyridin-2-ylmethyl)sulfanyl]pyridin-2(1H)-oneHCID 86731532—

Reaction Steps

Prepared as described for 5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one (Intermediate 17) but using 2-chloromethylpyridine instead of 1-(chloromethyl)-4-ethylbenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-5b9f02e436f6481794f1f9c6d87229c8
Source noteuspto-grants-2015_11