Pyrazine, 2-(chloromethyl)- → HCID 86731539, compound

HRID 709044Notes

Reaction equation

HRID 709044 reaction equation
C(C1C=[CH:23][C:6]([CH2:7][S:8][C:9]2[CH:10]=[C:11]([O:19][CH2:20][O:21][CH3:22])[C:12](=[O:18])[N:13]([CH2:15][O:16][CH3:17])[CH:14]=2)=CC=1)C.ClC[C:27]1[CH:32]=[N:31]C=C[N:28]=1>>[CH3:22][O:21][CH2:20][O:19][C:11]1[C:12](=[O:18])[N:13]([CH2:15][O:16][CH3:17])[CH:14]=[C:9]([S:8][CH2:7][C:6]2[CH:23]=[N:31][CH:32]=[CH:27][N:28]=2)[CH:10]=1

Participants

3

Reactant 2

HCID 170169Pyrazine, 2-(chloromethyl)-HCID 867315275-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one2×

Product 1

HCID 86731539HCID 86731539, compound

Procedure

Prepared as described for 5-[(4-ethylbenzyl)sulfanyl]-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one (Intermediate 17) but using 2-chloromethylpyrazine instead of 1-(chloromethyl)-4-ethylbenzene.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2b4dd2e525874cc7ac0521b2a12be83c
Source dataset
uspto-grants-2015_11
Patent number
US09180122B2

Reaction notes

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