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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709053Generated: October 30, 2026

1-Fluoro-2-iodobenzene → 5-[(2-Fluorophenyl)ethynyl]-2,3-dimethoxypyridine

https://huagongshe.com/reaction/709053

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Fluoro-2-iodobenzeneHCID 67673—
Reactant2,3-Dimethoxy-5-[(2-methylphenyl)ethynyl]pyridineHCID 71186209—
Product5-[(2-Fluorophenyl)ethynyl]-2,3-dimethoxypyridineHCID 71186352—

Reaction Steps

Prepared as described for 2,3-dimethoxy-5-[(2-methylphenyl)ethynyl]pyridine (Intermediate 33) but using 1-iodo-2-fluorobenzene instead of 1-iodo-2-methylbenzene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-9df1b812643946b8ac8c3886d874638f
Source noteuspto-grants-2015_11