2,3-Dimethoxy-5-[(1-phenylethyl)sulfanyl]pyridine → 3-Hydroxy-5-[(1-phenylethyl)sulfanyl]pyridin-2(1H)-one

HRID 709061Notes

Reaction equation

HRID 709061 reaction equation
C(SC1C=C(O)C(=O)NC=1)C1C=CC=CC=1.C[O:18][C:19]1[C:24]([O:25]C)=[CH:23][C:22]([S:27][CH:28]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH3:29])=[CH:21][N:20]=1>>[OH:25][C:24]1[C:19](=[O:18])[NH:20][CH:21]=[C:22]([S:27][CH:28]([C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH3:29])[CH:23]=1

Participants

3

Reactant 2

HCID 711861842,3-Dimethoxy-5-[(1-phenylethyl)sulfanyl]pyridine2×HCID 71187166HCID 71187166, compound

Product 1

HCID 711871513-Hydroxy-5-[(1-phenylethyl)sulfanyl]pyridin-2(1H)-one

Procedure

Prepared as described for 5-(benzylsulfanyl)-3-hydroxypyridin-2(1H)-one (Example 1) to from 2,3-dimethoxy-5-[(1-phenylethyl)sulfanyl]pyridine (Intermediate 9).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c6d49995cc5f4296bc1e149bf41526fc
Source dataset
uspto-grants-2015_11
Patent number
US09180122B2

Reaction notes

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