HCID 71187166, compound → 5-{[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}-3-hydroxypyridin-2(1H)-one

HRID 709070Notes

Reaction equation

HRID 709070 reaction equation
C(SC1C=C(O)C(=O)NC=1)C1C=CC=CC=1.[CH3:17][C:18]1[C:22]([CH2:23][S:24][C:25]2[CH:26]=[C:27]([O:35]COC)[C:28](=[O:34])[N:29](COC)[CH:30]=2)=[C:21]([CH3:39])[O:20][N:19]=1>>[CH3:17][C:18]1[C:22]([CH2:23][S:24][C:25]2[CH:26]=[C:27]([OH:35])[C:28](=[O:34])[NH:29][CH:30]=2)=[C:21]([CH3:39])[O:20][N:19]=1

Participants

3

Reactant 2

HCID 71187166HCID 71187166, compoundHCID 867315305-{[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one2×

Product 1

HCID 711861105-{[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}-3-hydroxypyridin-2(1H)-one

Procedure

Prepared as described for 5-(benzylsulfanyl)-3-hydroxypyridin-2(1H)-one (Example 12) from 5-{[(3,5-dimethyl-1,2-oxazol-4-yl)methyl]sulfanyl}-3-(methoxymethoxy)-1-(methoxymethyl)pyridin-2(1H)-one (Intermediate 20).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9c1447a77028491f98ad114a78422434
Source dataset
uspto-grants-2015_11
Patent number
US09180122B2

Reaction notes

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