HCID 71187166, compound → 3-Hydroxy-5-{[(2-methyl-1,3-oxazol-4-yl)methyl]sulfanyl}-pyridin-2(1H)-one

HRID 709071Notes

Reaction equation

HRID 709071 reaction equation
C(SC1C=C(O)C(=O)NC=1)C1C=CC=CC=1.COC[O:20][C:21]1[C:22](=[O:38])[N:23](COC)[CH:24]=[C:25]([S:27][CH2:28][C:29]2[N:30]=[C:31]([CH3:34])[O:32][CH:33]=2)[CH:26]=1>>[OH:20][C:21]1[C:22](=[O:38])[NH:23][CH:24]=[C:25]([S:27][CH2:28][C:29]2[N:30]=[C:31]([CH3:34])[O:32][CH:33]=2)[CH:26]=1

Participants

3

Reactant 2

HCID 71187166HCID 71187166, compoundHCID 867315313-(Methoxymethoxy)-1-(methoxymethyl)-5-{[(2-methyl-1,3-oxazol-4-yl)methyl]sulfanyl}pyridin-2(1H)-one2×

Product 1

HCID 711873213-Hydroxy-5-{[(2-methyl-1,3-oxazol-4-yl)methyl]sulfanyl}-pyridin-2(1H)-one

Procedure

Prepared as described for 5-(benzylsulfanyl)-3-hydroxypyridin-2(1H)-one (Example 12) from 3-(methoxymethoxy)-1-(methoxymethyl)-5-{[(2-methyl-1,3-oxazol-4-yl)methyl]sulfanyl}pyridin-2(1H)-one (Intermediate 21).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1ce000c999944420b7d1be9752e5928a
Source dataset
uspto-grants-2015_11
Patent number
US09180122B2

Reaction notes

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