HCID 71187166, compound → HCID 71187224, compound

HRID 709078Notes

Reaction equation

HRID 709078 reaction equation
C(SC1C=C(O)C(=O)NC=1)C1C=CC=CC=1.COC[O:20][C:21]1[C:22](=[O:38])[N:23](COC)[CH:24]=[C:25]([S:27][CH2:28][C:29]2[CH:34]=[N:33][CH:32]=[CH:31][N:30]=2)[CH:26]=1>>[OH:20][C:21]1[C:22](=[O:38])[NH:23][CH:24]=[C:25]([S:27][CH2:28][C:29]2[CH:34]=[N:33][CH:32]=[CH:31][N:30]=2)[CH:26]=1

Participants

3

Reactant 2

HCID 71187166HCID 71187166, compoundHCID 86731539HCID 86731539, compound2×

Product 1

HCID 71187224HCID 71187224, compound

Procedure

Prepared as described for 5-(benzylsulfanyl)-3-hydroxypyridin-2(1H)-one (Example 12) from 3-(methoxymethoxy)-1-(methoxymethyl)-5-[(pyrazin-2-ylmethyl)sulfanyl]pyridin-2(1H)-one (Intermediate 29).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-86ce179d920a423088c6bbd828661411
Source dataset
uspto-grants-2015_11
Patent number
US09180122B2

Reaction notes

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