Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709082Generated: October 28, 2026

2,3-Dimethoxy-5-[(3-methyl-phenyl)ethynyl]pyridine → 3-Hydroxy-5-[2-(3-methylphenyl)ethyl]pyridin-2(1H)-one

https://huagongshe.com/reaction/709082

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dimethoxy-5-[(3-methyl-phenyl)ethynyl]pyridineHCID 71186030—
Reactant3-hydroxy-5-(2-methylphenethyl)pyridin-2(1H)-oneHCID 71187170—
Product3-Hydroxy-5-[2-(3-methylphenyl)ethyl]pyridin-2(1H)-oneHCID 71186321—

Reaction Steps

Prepared as described for 3-hydroxy-5-(2-methylphenethyl)pyridin-2(1H)-one (Example 27) from 2,3-dimethoxy-5-[(3-methyl-phenyl)ethynyl]pyridine (Intermediate 34).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-247671e304ba4f8fb88346462c62799f
Source noteuspto-grants-2015_11