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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709083Generated: October 29, 2026

2,3-Dimethoxy-5-[(4-methylphenyl)ethynyl]pyridine → 3-Hydroxy-5-[2-(4-methylphenyl)ethyl]pyridin-2(1H)-one

https://huagongshe.com/reaction/709083

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dimethoxy-5-[(4-methylphenyl)ethynyl]pyridineHCID 71185960—
Reactant3-hydroxy-5-(2-methylphenethyl)pyridin-2(1H)-oneHCID 71187170—
Product3-Hydroxy-5-[2-(4-methylphenyl)ethyl]pyridin-2(1H)-oneHCID 71186360—

Reaction Steps

Prepared as described for 3-hydroxy-5-(2-methylphenethyl)pyridin-2(1H)-one (Example 27) from 2,3-dimethoxy-5-[(4-methylphenyl)ethynyl]pyridine (Intermediate 35).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09180122B2
Source datasetuspto-grants-2015_11
ORD IDord-ead3b9b4e0ce411ca8b508f3359395dc
Source noteuspto-grants-2015_11