HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-[(2-Fluorophenyl)ethynyl]-2,3-dimethoxypyridine → 5-[2-(2-Fluorophenyl)ethyl]-3-hydroxypyridin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-[(2-Fluorophenyl)ethynyl]-2,3-dimethoxypyridine | HCID 71186352 | — |
| Reactant | 3-hydroxy-5-(2-methylphenethyl)pyridin-2(1H)-one | HCID 71187170 | — |
| Product | 5-[2-(2-Fluorophenyl)ethyl]-3-hydroxypyridin-2(1H)-one | HCID 71187253 | — |
Reaction Steps
Prepared as described for 3-hydroxy-5-(2-methylphenethyl)pyridin-2(1H)-one (Example 27) from 5-[(2-fluorophenyl)ethynyl]-2,3-dimethoxypyridine (Intermediate 38).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09180122B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-da1e5e13da5f4b7a973de11e065c9945 |
| Source note | uspto-grants-2015_11 |