Nitromethane → HCID 59536845, compound

Participants

Reaction Steps

263 μl (1.51 mmol) of N,N-diisopropylethylamine were added to 10.1 ml (186 mmol) of nitromethane, and the yellow solution was stirred at RT for 1 h. 1.38 g (5.03 mmol) of the compound of Example 22A were then added, and the mixture was stirred at RT overnight. All volatile components were removed on a rotary evaporator. The residue was purified by preparative HPLC [Method 12]. This gave 865 mg (51% of theory) of the title compound.

Provenance & Evidence