Bis(pinacolato)diborane → HCID 178431083, compound

Participants

Reaction Steps

The title compound (624 mg, 61.5 mmol) was prepared from (+/−)-2-({trans-4-[(4-bromophenoxy)methyl]cyclohexyl}oxy)tetrahydro-2H-pyran (900 mg, 2.44 mmol) and bis(pinacolato)diborane (742 mg, 2.92 mmol) by a procedure analogous to that described for (+/−)-2-[(cis-4-{[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl}cyclohexyl)oxy]tetrahydro-2H-pyran, Example 8, Step D. 1H NMR (400 MHz, CHLOROFORM-d) δ ppm 1.03-1.63 (m, 20H) 1.65-1.90 (m, 3H) 1.90-2.01 (m, 2H) 2.03-2.15 (m, 2H) 3.45-3.55 (m, 1H) 3.55-3.67 (m, 1H) 3.72-3.85 (m, 2H) 3.89-3.97 (m, 1H) 4.70-4.79 (m, 1H) 6.88 (d, J=8.78 Hz, 2H) 7.74 (d, J=8.78 Hz, 2H)

Provenance & Evidence