Geranylacetone → (6S)-6,10-dimethylundecan-2-one

Participants

Reaction Steps

Specifically, it has been found that using the R-isomer of catalyst of formula (I) in the hydrogenation of E-geranyl acetone (=(E)-6,10-dimethylundeca-5,9-dien-2-one) the hydrogenation product (6S)-6,10-dimethylundecan-2-one is formed in more than 98% in respect to all of the possible stereoisomers (i.e. (6S)-6,10-dimethylundecan-2-one and (6R)-6,10-dimethylundecan-2-one) whereas the corresponding R-isomer is obtained only in amount of less than 2%.

Provenance & Evidence