1,4-Bis(dihydroquinidine)phthalazine → HCID 71556737, compound

Participants

Reaction Steps

Compound 6 was prepared according the same procedure described in Example 1 for preparing compound 4 using Ad-mix-β (Aldrich) as a starting material. Compound 6 was obtained as a yellow solid (70%): 1H-NMR (400 MHz, CD3OD): δ 8.37 (s, 1H), 8.04 (1H, dd, 2.6 & 8.6 Hz), 7.64 (1H, d, 7.8 Hz), 7.43-7.51 (m, 4H), 7.25-7.28 (m, 2H), 7.04-7.14 (m, 3H), 5.03 (dd, 1H, 0.6 & 4.6 Hz), 4.41 (d, 1H, 4.6 Hz), 4.0 (q, 2H, 7.0 Hz), 1.01 (t, 3H, 7.0 Hz); LC/MS: m/z=507.1 [M+Na+](Calc: 486.4).

Provenance & Evidence