反应详情

To a solution of ethyl 2-((3-(benzyloxy)phenyl)(ethyl)amino)acetate (960 mg) in methanol (30 mL) was added 10% palladium-activated carbon (300 mg) and, under a hydrogen atmosphere, the mixture was stirred at room temperature for 12 hr. The reaction mixture was filtered, and the filtrate was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (360 mg) as a colorless oil.

1. filtrationThe reaction mixture was filtered
2. customthe filtrate was evaporated under reduced pressure
3. customThe residue was purified by silica gel column chromatography (ethyl acetate/hexane)