Ethyl 3-(3-(benzyloxy)-5-methoxyphenyl)acrylate → Ethyl 3-(3-hydroxy-5-methoxyphenyl)propanoate

Participants

Reaction Steps

To a solution of ethyl 3-(3-(benzyloxy)-5-methoxyphenyl)acrylate (6.00 g) in methanol (100 mL) was added 10% palladium-activated carbon (500 mg) was added, and the mixture was stirred for 15 hr under a hydrogen atmosphere. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (4.00 g) as a colorless oil.

Provenance & Evidence