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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 709860Generated: November 1, 2026

Trifluoroacetic acid → HCID 178471901, compound

https://huagongshe.com/reaction/709860

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 178470844HCID 178470844—
ReactantHCID 178471902HCID 178471902—
ProductHCID 178471901HCID 17847190120%

Reaction Steps

2-Amino-2-[6-(trans-4-tert-butyl-cyclohexyloxy)-5-trifluoromethyl-quinolin-2-yl]-propionic acid ethyl ester was synthesized as per 2-amino-2-[6-(trans-4-tert-butyl-cyclohexyloxy)-quinolin-2-yl]-propionic acid ethyl ester (Example 17) in 20% yield (TFA salt) using 2-[6-(trans-4-tert-Butyl-cyclohexyloxy)-5-trifluoromethyl-quinolin-2-yl]-2-nitro-propionic acid ethyl ester as starting material.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181191B2
Source datasetuspto-grants-2015_11
ORD IDord-b5af3b056c3c400e85a2da0367a5fc2b
Source noteuspto-grants-2015_11