HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178453525, compound → HCID 178453569, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178453525 | HCID 178453525 | — |
| Reactant | HCID 178453572 | HCID 178453572 | — |
| Product | HCID 178453569 | HCID 178453569 | 68% |
Reaction Steps
[1-[6-(trans-4-tert-Butyl-cyclohexyloxy)-5-trifluoromethyl-quinolin-2-yl]-2-(di-tert-butoxy-phosphoryloxy)-1-methyl-ethyl]-carbamic acid tert-butyl ester Enantiomer 1 was synthesized as per [1-[6-(trans-4-tert-Butyl-cyclohexyloxy)-quinolin-2-yl]-2-(di-tert-butoxy-phosphoryloxy)-1-methyl-ethyl]-carbamic acid tert-butyl ester Enantiomer 1 (Example 29) in 68% yield using {1-[6-(trans-4-tert-Butyl-cyclohexyloxy)-5-trifluoromethyl-quinolin-2-yl]-2-hydroxy-1-methyl-ethyl}-carbamic acid tert-butyl ester Enantiomer 1 as starting material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181191B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-d048ab25950d415295e9938454adb81e |
| Source note | uspto-grants-2015_11 |