反应详情

To a toluene (112 mL) solution of the compound (5.87 g) obtained in Example 9-(1), Burgess reagent (5.322 g) was added and the mixture was heated under reflux for 2.5 hours. The reaction mixture was concentrated to give a crude product, which was further purified by silica gel chromatography (AcOEt/hexane) to give the titled compound (4.151 g, colorless amorphous.)

1. temperaturethe mixture was heated
2. temperatureunder reflux for 2.5 hours
3. concentrationThe reaction mixture was concentrated
4. customto give a crude product, which
5. customwas further purified by silica gel chromatography (AcOEt/hexane)