反应详情

温度

90 °C

To a toluene (30 ml) solution of the compound (540 mg) obtained in Example 8-(1), Lawesson's reagent (750 mg) was added and the mixture was stirred at 90° C. for 6 hours. After adding water, extraction was conducted with AcOEt. The solvent was distilled off under reduced pressure and the residue was purified by silica gel chromatography (AcOEt/hexane) to give the titled compound (291 mg).

1. additionAfter adding
2. extractionwater, extraction
3. distillationThe solvent was distilled off under reduced pressure
4. customthe residue was purified by silica gel chromatography (AcOEt/hexane)