Sodium Azide → HCID 178505415, compound

Participants

Reaction Steps

2-Fluoro-4-bromobenzonitrile (300 mg, 1.5 mmol) dissolved in EtOH, added sodium azide (320 mg, 4.9 mmol), Zinc chloride (240 mg, 1.8 mmol). This mixture was stirred refluxed for 38 h. Work up (EtOAc/H2O) afforded the crude. Crude was washed with petether to obtain the titled compound (120 mg) as a white solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.89-7.79 (m, 1H), 7.59 (dd, J 1.6, 10.04, 1H), 7.45 (dd, J 1.8, 8.3, 1H).

Provenance & Evidence