HRID710118

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1(C)OB(c2ccc(S(C)(=O)=O)cc2F)OC1(C)C

HCID68299298

未命名化合物

结构：CC(C)(C)OC(=O)N1CCC(c2nc3ccc(Br)cc3o2)CC1

HCID71089554

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCC(c2nc3ccc(-c4ccc(S(C)(=O)=O)cc4F)cc3o2)CC1

HCID71114582

未命名化合物

收率 17%

PROCEDURE

实验过程

Following the General Procedure-1, the titled compound (21 mg) was prepared from Intermediate 10 (100 mg, 0.26 mmol) and Intermediate 3 (102 mg, 0.34 mmol) as an off-white solid. M.P.: 174-178.3° C. 1H-NMR (δ ppm, CDCl3, 400 MHz): 7.85-7.75 (m, 3H), 7.73-7.64 (m, 2H), 7.50 (d, J 8.2, 1H), 4.15 (d, J 12.4, 2H), 3.20-3.10 (m, 4H), 3.0 (t, J 12.5, 2H), 2.20-2.12 (m, 2H), 2.00-1.85 (m, 2H), 1.48 (s, 9H).