1-(4-bromo-3-fluorophenyl)-1H-tetrazole → HCID 71114194, Verbindung

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-(4-bromo-3-fluorophenyl)-1H-tetrazole	HCID 23122179	—
Edukt	Tert-butyl 4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2-yl)piperidine-1-carboxylate	HCID 71090269	—
Produkt	HCID 71114194	HCID 71114194	4,8%

Reaktionsschritte

Following the General Procedure-1, the titled compound (10 mg) was prepared from Intermediate 8 (200 mg, 0.47 mmol) and 1-(4-bromo-3-fluorophenyl)-1H-tetrazole (110 mg, 0.45 mmol) as a brown solid. M.P.: 203-207° C. 1H-NMR (δ ppm, CDCl3, 400 MHz): 9.04 (s, 1H), 7.88 (s, 1H), 7.71-7.58 (m, 4H), 7.52 (td, 1.6, 8.4, 1H), 4.16 (d, J 10.8, 2H), 3.21-3.12 (m, 1H), 3.00 (t, J 12.2, 2H), 2.21-2.13 (m, 2H), 2.00-1.85 (m, 2H), 1.48 (s, 9H).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US09181214B2
Quelldatensatz	uspto-grants-2015_11
ORD ID	ord-1aa784af6a0e443baeae07a475a1b863
Quellennotiz	uspto-grants-2015_11