HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3-Fluoro-4-(isopropylcarbamoyl)phenyl)boronic acid → Isopropyl 4-{5-[3-fluoro-4-(isopropylcarbamoyl)phenyl]benzo[d]oxazol-2-yl}piperidine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3-Fluoro-4-(isopropylcarbamoyl)phenyl)boronic acid | HCID 44717484 | — |
| Edukt | Isopropyl 4-(5-bromobenzo[d]oxazol-2-yl)piperidine-1-carboxylate | HCID 71257568 | — |
| Produkt | Isopropyl 4-{5-[3-fluoro-4-(isopropylcarbamoyl)phenyl]benzo[d]oxazol-2-yl}piperidine-1-carboxylate | HCID 71257559 | 17,8% |
Reaktionsschritte
Following the General Procedure-3, the titled compound (45 mg) was prepared from Intermediate 13 (200 mg, 0.54 mmol) and 3-fluoro-4-(isopropylcarbamoyl)phenylboronic acid (120 mg, 0.54 mmol) as a grey solid. M.P.: 147-150° C. MS (m/z): 468.4 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09181214B2 |
| Quelldatensatz | uspto-grants-2015_11 |
| ORD ID | ord-fc557aac15374be6b04ad47b41546edb |
| Quellennotiz | uspto-grants-2015_11 |