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HRID710195

反应详情

EQUATION

反应方程式

HRID 710195 的结构方程式

REACTANTS

反应物

2
结构：CC#CCOc1cnc(C(=O)O)cn1
HCID58448677

未命名化合物

结构：C[C@]1(c2cc(N)ccc2F)N=C(N)O[C@@H]2CCC(F)(F)[C@@H]21
HCID90021263

未命名化合物

PRODUCTS

生成物

1
结构：CC#CCOc1cnc(C(=O)Nc2ccc(F)c([C@@]3(C)N=C(N)O[C@@H]4CCC(F)(F)[C@@H]43)c2)cn1
HCID72706009

未命名化合物

PROCEDURE

实验过程

The coupling of (4S,4aR,7aR)-4-(5-amino-2-fluoro-phenyl)-5,5-difluoro-4-methyl-4,4a,5,6,7,7a-hexahydro-cyclopenta[e][1,3]oxazin-2-ylamine (intermediate XIIIa-1) and 5-but-2-ynyloxy-pyrazine-2-carboxylic acid (CAS 1221447-98-814) following procedure Q yielded the title compound as an amorphous colorless material (34% yield). MS: m/z=474.2 [M+H]+.