反应详情

[Bis(trifluoroacetoxy)iodo]benzene (90.5 mg, 0.211 mmol) was dissolved in chloroform (5 ml), then (S)-tert-butyl 2-(4-((2-(4-fluorobenzoyl)hydrazono)methyl)phenyl)morpholine-4-carboxylate (75 mg, 0.175 mmol) was added and the mixture was stirred at room temperature for 20 min. The solvent was evaporated and the residue was purified by flash chromatography (10 g silica gel, 10 to 20% ethyl acetate in heptane) to yield a white solid (49 mg, 66%). MS (ISP): 370.1 ([M-tBu+H]+), 426.1 ([M+H]+).

1. customThe solvent was evaporated
2. customthe residue was purified by flash chromatography (10 g silica gel, 10 to 20% ethyl acetate in heptane)