Hydrochloric Acid → HCID 89689458, compound

Participants

Reaction Conditions

Reaction Steps

(R)-tert-Butyl 2-(2-(6-ethoxypyridin-3-yl)benzo[d]oxazol-6-yl)morpholine-4-carboxylate (31 mg, 0.073 mmol) was dissolved in dioxane (0.3 ml). Then a solution of HCl in dioxane (4M, 0.27 ml, 1.09 mmol) was added and the reaction mixture was stirred at 60° C. for 2 hours. After cooling, the solid was filtered off and washed with diethylether and dried in vacuo to afford (R)-2-(6-ethoxypyridin-3-yl)-6-(morpholin-2-yl)benzo[d]oxazole hydrochloride (15 mg, 58%) as a light yellow solid. MS (ISP): 326.6 ([M+H]+).

Provenance & Evidence