反应详情

When the product of Step C is substituted for 5-(oct-1-ynyl)-2-tritylisoindoline in Example 2, Step E, the identical process afforded the title compound in 90% yield, as a colourless foam. 1H-NMR (CDCl3) 0.86 (tr, 3H, J=6.9 Hz); 1.24 (m, 10H); 1.42 (m, 15H); 1.91 (m, 2H); 2.43 (tr, 2H, J=8 Hz); 2.75 (tr, 2H, J=6.5 Hz); 3.25 (tr, 1H, J=5.5 Hz); 3.64 (s, 2H); 3.8-3.99 (m, 4H); 4.7 (s, 1H); 6.7 (d, 1H, J=8.4 Hz); 6.76 (s, 1H); 6.82 (d, 1H, J=8.4 Hz).