tert-Butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate → HCID 46196021, compound

Participants

Reaction Steps

When the product of Step F was substituted for tert-butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 34, Step E, the identical process afforded the title compound in 54% yield, as a fluffy white solid. 1H-NMR (DMSO-d6) 0.99 (tr, 3H, J=7.4 Hz); 1.74-1.81 (m, 2H); 3.03 (s, 2H); 3.27-3.32 (m, 6H); 3.53 (rt, 2H, J=8.03 Hz); 4.73 (m, 2H); 6.78 (d, 1H, J=7.8 Hz); 7.14 (tr, 1H, J=7.78 Hz); 7.25 (d, 1H, J=7.12 Hz); 7.36 (d, 1H, J=8.72 Hz); 8.0 (d, 1H, J=8.31 Hz); 8.11 (d, 1H, J=3.4 Hz).

Provenance & Evidence