tert-Butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate → HCID 46195602, compound

Participants

Reaction Steps

When the product of Step E was substituted for tert-butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 34, Step E, the identical process afforded the title compound in 52% yield. 1H-NMR (DMSO-d6) 0.92 (tr, 3H, J=7.47 Hz); 1.07-1.48 (m, 2H); 1.71-1.76 (m, 2H); 2.98 (s, 2H); 3.22-3.56 (m, 8H); 4.17 (tr, 2H, J=6.36 Hz); 4.62 (m, 2H); 6.76 (d, 1H, J=7.74 Hz); 7.13 (tr, 1H, J=7.83 Hz); 7.24 (d, 1H, J=7.17 Hz); 7.37 (d, 1H, J=8.79 Hz); 8.07 (dd, 1H, J=2.13, 8.64 Hz); 8.12 (d, 1H, J=2.13 Hz).

Provenance & Evidence