5-(3,4-Diethoxyphenyl)-3-(1H-indol-4-yl)-1,2,4-oxadiazole → 5-(4-Ethoxy-3-methoxyphenyl)-3-(indolin-4-yl)-1,2,4-oxadiazole

Participants

Reaction Steps

When the product of Step C was substituted for 5-(3,4-diethoxyphenyl)-3-(1H-indol-4-yl)-1,2,4-oxadiazole in Example 34, Step C, the identical process afforded the title compound 100% yield. 1H-NMR (CDCl3) 1.5 (tr, 3H, J=3.98 Hz); 3.6 (tr, 2H, J=7.79 Hz); 3.8 (tr, 2H, J=8.87 Hz); 3.99 (s, 3H); 4.19 (q, 2H, J=14, 7 Hz); 6.97 (d, 1H, J=8.5 Hz); 7.17 (d, 1H, J=7.79 Hz); 7.32 (tr, 1H, J=7.82 Hz); 7.66 (d, 1H, J=1.92 Hz); 7.67 (dd, 1H, J=1.97, 8.41 Hz), 7.89 (d, 1H, J=7.78 Hz).

Provenance & Evidence