tert-Butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate → HCID 46195321, compound

Participants

Reaction Steps

When the product of Step E was substituted for tert-butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 34, Step E, the identical process afforded the title compound in 83% yield, as white solid. 1H-NMR (CDCl3: CD3OD) 1.43 (tr, 3H, J=6.98 Hz); 3.14 (s, 2H); 3.24-3.5 (m, 4H); 3.58 (d, 2H, J=11.87 Hz); 3.64 (d, 2H, J=11.63 Hz); 3.91 (s, 3H); 4.1 (q, 2H, J=14, 7.02 Hz); 6.75 (d, 1H, J=7.78 Hz); 6.91 (d, 1H, J=8.54 Hz); 7.17 (tr, 1H, J=7.98 Hz); 7.41 (d, 1H, J=7.75 Hz), 7.6 (s, 1H); 7.71 (d, 1H, J=1.86, 8.49 Hz).

Provenance & Evidence