tert-Butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate → HCID 46195742, compound

Participants

Reaction Steps

When the product of Step E was substituted for tert-butyl 5-((4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)indolin-1-yl)methyl)-2,2-dimethyl-1,3-dioxan-5-ylcarbamate in Example 34, Step E, the identical process afforded the title compound in 44% yield. 1H-NMR (DMSO-d6) 1.0 (tr, 3H, J=7.38 Hz); 1.75-1.79 (m, 2H); 2.99 (5, 2H); 3.2-3.4 (m, 8H); 4.13 (tr, 2H, J=6.30 Hz); 4.61 (broad s, 1H); 6.77 (d, 1H); 7.13 (tr, 1H); 7.24 (d, 1H, J=7.59 Hz), 7.31 (d, 1H, J=8.79 Hz), 8.11 (dd, 1H, J=2.13, 8.64 Hz), 8.27 (d, 1H, J=2.46 Hz).

Provenance & Evidence